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Electrochemical Determination of Tyrosine Using Graphene and Gold Nanoparticle Composite Modified Glassy Carbon Electrode

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Abstract

A electrochemical sensor based on graphene and gold nanoparticles modified glassy carbon electrode (GCE) was developed for the determination of tyrosine (Tyr). The graphene and gold nanoparticles modified glassy carbon electrode (GR/Au NPs/GCE) was prepared by potentiostatic deposition of gold nanoparticles on the grephene coated GCE. Cyclic voltammetry and linear sweep voltammetry were used to study the electrochemical behavior of Tyr on the modified electrode, which showed improved electrocatalytic behavior for oxidation of Tyr due to the significant enhancement of peak current. A linear response between the peak current and the Tyr concentration was detected between 100 nM–100 μM and the detection limit (S/N = 3) was 47 nM. The simple preparation and the good sensitivity make this graphene/gold nanoparticles modified GCE very promising for Tyr analysis in real samples.

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ACKNOWLEDGMENTS

This work was financially supported by National Natural Science Foundation of China (no. 21505035), Scientific Research Projects of Education Department of Hunan Province (no. 19K011, no. 18A336), Hunan Hengyang Science and Technology Plan Preject (2019jhzx0741), Research Project of Hengyang Normal University (no. 18XKQ01, GN19K04) and Environmental Monitoring and Evaluation Center of Hengyang Normal University (KYJG1803).

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Authors and Affiliations

  1. Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Hengyang Normal University, 421008, Hengyang, PR China

    M. Liu, H. Wang, Z. Xu, J. Li, L. Wen & Z. Yin

  2. Hunan Province Universities Key Laboratory of Functional Organometallic Materials, College of Chemistry and Material Science, Hengyang Normal University, 421008, Hengyang, PR China

    M. Liu, H. Wang, Z. Xu, J. Li, L. Wen & Z. Yin

  3. Key Laboratory of Polar Materials and Devices (MOE), Department of Electronics, East China Normal University, 200241, Shanghai, China

    J. Lao, C. Luo & H. Peng

  4. Collaborative Innovation Center of Extreme Optics, Shanxi University, 030006, Taiyuan, Shanxi, China

    H. Peng

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  1. M. Liu
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Liu, M., Lao, J., Wang, H. et al. Electrochemical Determination of Tyrosine Using Graphene and Gold Nanoparticle Composite Modified Glassy Carbon Electrode. Russ J Electrochem 57, 41–50 (2021). https://doi.org/10.1134/S1023193520110063

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  • DOI: https://doi.org/10.1134/S1023193520110063

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