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Plant Proteases Involved in Regulated Cell Death

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Abstract

Each plant genome encodes hundreds of proteolytic enzymes. These enzymes can be divided into five distinct classes: cysteine-, serine-, aspartic-, threonine-, and metalloproteinases. Despite the differences in their structural properties and activities, members of all of these classes in plants are involved in the processes of regulated cell death–a basic feature of eukaryotic organisms. Regulated cell death in plants is an indispensable mechanism supporting plant development, survival, stress responses, and defense against pathogens. This review summarizes recent advances in studies of plant proteolytic enzymes functioning in the initiation and execution of distinct types of regulated cell death.

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Abbreviations

ER:

endoplasmic reticulum

NCCD:

Nomenclature Committee on Cell Death

PCD:

programmed cell death

PS-SCL:

positional scanning substrate combinatorial library

RCD:

regulated cell death

VPE:

vacuolar processing enzyme.

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  1. Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia

    A. A. Zamyatnin Jr.

  2. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991, Moscow, Russia

    A. A. Zamyatnin Jr.

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Original Russian Text © A. A. Zamyatnin, Jr., 2015, published in Uspekhi Biologicheskoi Khimii, 2015, Vol. 55, pp. 145-180.

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Zamyatnin, A.A. Plant Proteases Involved in Regulated Cell Death. Biochemistry Moscow 80, 1701–1715 (2015). https://doi.org/10.1134/S0006297915130064

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