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Synthesis of α-cyclopiazonic acid by fungi of the genus Aspergillus

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Abstract

The presence of α-cyclopiazonic acid has been studied among metabolites of Aspergillus fungi. The study was performed with 138 cultures of 13 species obtained from the All-Russia Collection of Microorganisms and the collection of our institute. α-Cyclopiazonic acid was most frequently encountered among the metabolites of the section Flavi (the ability to synthesize α-cyclopiazonic acid was expressed in 61% of the strains of A. flavus, 83% of the strains of A. oryzae, and all strains of A. tamarii). This expression index for A. versicolor was less than 5%. We showed for the first time that α-cyclopiazonic acid is produced by A. fumigatus and A. phoenicis (expression in 30% of the strains of either species).

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Authors and Affiliations

  1. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia

    N. G. Vinokurova, N. E. Ivanushkina, I. I. Khmel’nitskaya & M. U. Arinbasarov

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  1. N. G. Vinokurova
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  2. N. E. Ivanushkina
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  3. I. I. Khmel’nitskaya
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  4. M. U. Arinbasarov
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Original Russian Text © N.G. Vinokurova, N.E. Ivanushkina, I.I. Khmel’nitskaya, M.U. Arinbasarov, 2007, published in Prikladnaya Biokhimiya i Mikrobiologiya 2007, Vol. 43, No. 4, pp. 486–489.

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Vinokurova, N.G., Ivanushkina, N.E., Khmel’nitskaya, I.I. et al. Synthesis of α-cyclopiazonic acid by fungi of the genus Aspergillus . Appl Biochem Microbiol 43, 435–438 (2007). https://doi.org/10.1134/S0003683807040138

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  • DOI: https://doi.org/10.1134/S0003683807040138

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