The aim of this study was to propose simultaneous analysis of effective transverse relaxation time (T₂) and biexponential diffusion parameters for breast magnetic resonance imaging (MRI) using conventional sequences available with most clinical MRI scanners. Normal mammary glands and malignant lesions were compared in terms of T₂ value, as well as fast and slow component apparent diffusion coefficients (ADC_fast and ADC_slow) . The study included 98 women who underwent breast MRI and for whom pathological diagnosis was obtained. Diffusion weighted imaging (DWI) was performed at b values of 0, 200, 400, 800, 1500, 2200, and 3000s/mm². The T₂ correction of DW images were performed using diffusion echo-planar imaging-T₂-weighted images with multiple TE because TE increased with increasing b values. Biexponential fitting was performed using the b value range of 0-3000s/mm² for malignant lesions, and 0-1500s/mm² for normal mammary glands, to minimize the influence of noise. Malignant lesions showed significantly higher T₂ values, lower ADC_fast and ADC_slow compared with normal mammary glands. In addition, fast component fraction was significantly higher in malignant lesions than in normal mammary glands. In conclusion, simultaneous T₂ and biexponential diffusion analyses can provide more detailed information on the characteristics of breast lesions.