DETECTION OF DNA FRAGMENTATION IN γ-IRRADIATED RAT TONGUE EPITHEIUM

Motoaki YASUDA; Takeshi NISHIOKA; Hiroki SHIRATO; Motoyasu NAKAMURA

doi:10.11182/jastro1989.8.63

Motoaki YASUDA, Takeshi NISHIOKA, Hiroki SHIRATO, Motoyasu NAKAMURA

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Keywords: Apoptosis, TdT (terminal deoxynucleotidyl transferase), γ-irradiation, Rat tongue epithelium

JOURNAL FREE ACCESS

1996 Volume 8 Issue 1 Pages 63-66

DOI https://doi.org/10.11182/jastro1989.8.63

[Correction] The Journal of JASTRO Vol.8 No.2 (1996) pp.179-179

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Abstract

Apoptosis is the predominant form of cell death and occurs under variety of physiological and pathological conditions. In the present study, we detected the apoptotic cells and S phase cells in rat tongue epithelium in both normal and irradiated conditions. After 24 hours from irradiation, cell cycle arrest was obvious and the number of apoptotic cell reached the maximum level; however there was no detectable DNA fragmentation in basal cells.

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