Molecular recognition of functionalized polydiacetylene and its biosensor

Yajun Li; Yi Fan; Ligong Zhang; Shaojie Ma; Jiayin Zheng

doi:10.1117/12.385581

9 May 2000 Molecular recognition of functionalized polydiacetylene and its biosensor

Yajun Li, Yi Fan, Ligong Zhang, Shaojie Ma, Jiayin Zheng

Proceedings Volume 4077, International Conference on Sensors and Control Techniques (ICSC 2000); (2000) https://doi.org/10.1117/12.385581
Event: International Conference on Sensors and Control Techniques (ICSC2000), 2000, Wuhan, China

Abstract

Molecular recognition processes are very important in the investigation of biological phenomena as well as development of fiber optic biosensor. As promising materials, biofunctionalized polydiacetylene lipids have many special properties. p-10,12-pentacosadiyne-1-N-(3,6,9- trioxaundecylanide)-a-D-mannopyranoside (MPDA) was synthesized from 10,12-pentacasadiynoic acid (PDA). The mixed monolayer MPDA/PDA was prepared by using Langmuir- Blodgett technique on glass and optical fiber, respectively. Molecular recognition of Escherichia coli (E. coli) resulted in a change of the film color and can be quantified by UV- Visible absorption spectroscopy. The properties might be used for screening drugs and diagnosis.

Citation Download Citation

Yajun Li, Yi Fan, Ligong Zhang, Shaojie Ma, and Jiayin Zheng "Molecular recognition of functionalized polydiacetylene and its biosensor", Proc. SPIE 4077, International Conference on Sensors and Control Techniques (ICSC 2000), (9 May 2000); https://doi.org/10.1117/12.385581

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