A novel gravity valve and its application in a 3D printed centrifugal fluidic-system for solid phase extraction (SPE)

Yong Zhang; Jiwen Xiang; Yunxia Wang; Zheng Qiao; Wanjun Wang

doi:10.1117/12.2550845

25 February 2020 A novel gravity valve and its application in a 3D printed centrifugal fluidic-system for solid phase extraction (SPE)

Yong Zhang, Jiwen Xiang, Yunxia Wang, Zheng Qiao, Wanjun Wang

Author Affiliations +

Proceedings Volume 11235, Microfluidics, BioMEMS, and Medical Microsystems XVIII; 112350I (2020) https://doi.org/10.1117/12.2550845
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

A 3D centrifugal cartridge with gravity valve, capillary valves, and Coriolis switching valve was designed, fabricated, and tested for Solid Phase Extraction (SPE). In particular, the novel three-dimensional gravity valve helps to release reagents in not-sequentially increased rotation speeds. The sequential control of these valves was simply achieved by manipulating the rotating direction and speed of the cartridge. The prototype microfluidic cartridge was 3D printed with a FDM printer and experimentally tested. Anthracene, which was one of the Polycyclic Aromatic Hydrocarbons (PAHs), was used as the target analyte and tested. C18 was used as the stationary sorbent and fluorescence method was adopted to detect anthracene. The concentrations of the anthracene testing samples were 1μg/L (1ppb), 5μg/L, and 10μg/L (anthracene/water), respectively. The volumes of testing sample and eluent (nonane) were 10mL and 1mL respectively. Experiments showed that 7 times of enrichment of the original samples were achieved. This centrifugal SPE system could be potentially used as a portable on-situ pollutant enrichment and detection device.

Conference Presentation

Citation Download Citation

Yong Zhang, Jiwen Xiang, Yunxia Wang, Zheng Qiao, and Wanjun Wang "A novel gravity valve and its application in a 3D printed centrifugal fluidic-system for solid phase extraction (SPE)", Proc. SPIE 11235, Microfluidics, BioMEMS, and Medical Microsystems XVIII, 112350I (25 February 2020); https://doi.org/10.1117/12.2550845

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available