Transurethral radio-frequency ablation of the prostate

John N. Kabalin M.D.

doi:10.1117/12.239991

17 May 1996 Transurethral radio frequency ablation of the prostate

John N. Kabalin M.D.

Proceedings Volume 2671, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI; (1996) https://doi.org/10.1117/12.239991
Event: Photonics West '96, 1996, San Jose, CA, United States

Abstract

Since 1993, radiofrequency ablation of the prostate has been studied as a potential treatment for symptomatic bladder outlet obstruction due to benign prostatic hyperplasia. Two transurethral radiofrequency delivery systems have been developed to the point of undergoing initial human clinical trials. The TUNA^TM system involves focal interstitial radiofrequency energy application, while the TURAPY^TM system involves a circumferential application of radiofrequency energy to the prostatic urethra via a simple delivery catheter. Experimental studies in animal models and human prostate tissue have demonstrated the nature of radiofrequency induced tissue heating and thermal injury. Observed thermal effects are relatively focused, with steep temperature gradients occurring over a few millimeters from the radiofrequency emission source. This allows precise and focused tissue treatment with little or no danger of injury to surrounding structures. Early human clinical experience in the treatment of benign prostatic hyperplasia has demonstrated efficacy in the relief of voiding symptoms and safety and minimal morbidity associated with this technology. The existing operative approaches are relatively simple. Ongoing development of more versatile delivery systems for radiofrequency ablation of the prostate is expected. Results from larger clinical trials with longer term followup will eventually allow adequate assessment of the role of radiofrequency ablation in the surgical management of benign prostatic hyperplasia.

Citation Download Citation

John N. Kabalin M.D. "Transurethral radio frequency ablation of the prostate", Proc. SPIE 2671, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI, (17 May 1996); https://doi.org/10.1117/12.239991

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