Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement

Olga S. Godage; Alla B. Bucharskaya; Nikita A. Navolokin; Sergey V. German; Viktor V. Zuev; Georgy S. Terentyuk; Galina N. Maslyakova; Dmitry A. Gorin

doi:10.1117/12.2229872

21 April 2016 Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement

Olga S. Godage, Alla B. Bucharskaya, Nikita A. Navolokin, Sergey V. German, Viktor V. Zuev, Georgy S. Terentyuk, Galina N. Maslyakova, Dmitry A. Gorin

Author Affiliations +

Proceedings Volume 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS); 99171H (2016) https://doi.org/10.1117/12.2229872
Event: Saratov Fall Meeting 2015, 2015, Saratov, Russian Federation

Abstract

Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus , the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries , as well as their impact on the organs and tissues as results of nanostructured object biodistribution.

Citation Download Citation

Olga S. Godage, Alla B. Bucharskaya, Nikita A. Navolokin, Sergey V. German, Viktor V. Zuev, Georgy S. Terentyuk, Galina N. Maslyakova, and Dmitry A. Gorin "Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement ", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 99171H (21 April 2016); https://doi.org/10.1117/12.2229872

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available