Rearrangements of Genetic Material in Escherichia coli As Observed on the Bacteriophage P1 Plasmid
This extract was created in the absence of an abstract.
Excerpt
IS elements (Starlinger and Saedler 1976; Bukhari et al. 1977) play an important role in structural rearrangements of genetic materials, particularly because of their ability to transpose, either alone or together with linked genetic materials, and to generate deletions and inversions. Possibly, IS elements and transposons (transposable, or Tn, elements) are widespread in nature, and in addition to being driving forces in evolution, they may fulfill yet unknown important functions.
Most, if not all, IS and Tn elements characterized thus far were found by chance. Therefore, it would be helpful to design a more systematic approach to identifying Tn elements in view of collecting information on the number of different such elements carried by each particular organism. The establishment of a library of IS elements is also important to studies on the structure and function of IS elements and should provide clues as to how universal particular IS elements are...
