Case ReportsHigh-Grade Neuroendocrine Carcinoma of the Lung Presenting an Unusual Spread Mimicking Pleural Mesothelioma Associated with Dermatomyositis
Section snippets
Case Report
A 52-year-old man was admitted to our hospital because of pain and muscle weakness in the right arm. The patient had been well until 4 months earlier, when he began to have facial erythema and erythematous scaly plaque on the dorsal hands. One month later, he felt paresthesias in the third and fourth fingers of the right hand and pain in the right shoulder and arm. Two weeks before admission, he noted debilitating weakness, especially with the ability to grip his right hand. He had no history
Discussion
The high-grade NECs include not only SCCs but LCNECs. Studies with immunocytochemical and molecular methods support the concept that the high-grade NECs of the lung are a common group of neoplasms, distinct from carcinoid tumor. Uncertainty over the diagnosis of SCCs or LCNECs emerges because of their markedly overlapping cytological features as well as the subjectivity of diagnostic criteria. In addition, it is controversial whether the distinction between SCC and LCNEC has clinical value, in
References (8)
- et al.
Lung cancer
Lancet
(2000) - et al.
Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases
Ann Diagn Pathol
(1999) Dermatomyositis
Lancet
(2000)- et al.
Pseudomesotheliomatous carcinoma of the lung: a variant of peripheral lung cancer
Am J Clin Pathol
(1976)
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2017, Lung CancerCitation Excerpt :The presences of positive anti-nuclear antibody (ANA) and of anti Jo-1 antibodies were not statistically correlated with malignancy. Case reports provided information in the context of lung cancer on 39 patients with dermatopolymyositis [219–252] and 4 with polymyositis [229,253–255]. Thirteen patients had SCLC (all associated with DM) and all the others had NSCLC, including a neuroendocrine lung cancer [232] and a carcinoid tumour [244].
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