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Anthony L. Komaroff, Dedra Buchwald, Symptoms and Signs of Chronic Fatigue Syndrome, Reviews of Infectious Diseases, Volume 13, Issue Supplement_1, January-February 1991, Pages S8–S11, https://doi.org/10.1093/clinids/13.Supplement_1.S8
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Abstract
This review summarizes the symptoms and signs seen in patients with chronic fatigue syndrome (CFS). It is based on the authors' experience with two cohorts of ∼510 patients with chronic debilitating fatigue and on the reported experience of other investigators with similar patients. The most characteristic symptoms of CFS are the sudden onset of an infectious-type illness, the subsequent chronic and debilitating fatigue, and postexertional malaise; many patients also have recurrent fevers, pharyngitis, adenopathy, myalgias, sleep disorders, and cognitive impairment.
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