Effect of age on changes in plasma, erythrocyte, and urinary B-6 vitamers after an oral vitamin B-6 load

doi:10.1093/ajcn/48.5.1284

The American Journal of Clinical Nutrition

Volume 48, Issue 5, November 1988, Pages 1284-1290

https://doi.org/10.1093/ajcn/48.5.1284 Get rights and content

ABSTRACT

We investigated the effect of age on indices of vitamin B-6 metabolism in 36 fasting males aged 25–35, 45–55, and 65–75 y who ingested 17.15 mumol vitamin B-6. There were no significant differences among groups in dietary vitamin B-6 intake, base-line erythrocyte pyridoxal 5'-phosphate (PLP), and total vitamin B-6 concentrations, and 24-h and base-line urinary excretion of total vitamin B-6 and 4-pyridoxic acid (4-PA). Base-line plasma PLP and total vitamin B-6 were higher (p less than 0.05) in the youngest group. Increased serum alkaline phosphatase (AP) and decreased dietary vitamin B-6 intake were correlated with decreased base-line plasma PLP and total vitamin B-6. Changes in plasma and erythrocyte PLP concentrations and excretion of 4-PA and total vitamin B-6 postload were not different among groups. Indices of vitamin B-6 absorption, phosphorylation, and excretion were not affected by age.

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Effect of age on changes in plasma, erythrocyte, and urinary B-6 vitamers after an oral vitamin B-6 load

ABSTRACT

Am J Clin Nutr

Am J Clin Nutr

Clin Chim Acta

Am J Clin Nutr

Clin Chim Acta

Am J Clin Nutr

J Nutr

Am J Clin Nutr

J Nutr

Clin Chim Acts

Exp Gerontol

Vitamin B-6 status of the elderly in Mongtomery County, Va.

Nutr Rep Int

Evaluation ofpyridoxine intake and pyridoxine status among aged institutionalized people.

Int J Vitam Nutr Res

Problem nutrients in the United States.

Food Technol

A dietary survey ofolder people in Edinburgh.

Br J Nutr

Vitamin B-6 status of the elderly.

Vitamin B-6 deficiency in the aged.

J Gerontol

Biochemical evaluation of vitamin and iron status of an apparently healthy Dutch free living population-comparison with younger adults.

Int J Vitam Nutr Res