Abstract
Exhaled breath condensate (EBC) collection and analysis offers a unique non-invasive method to sample the airway lining fluid. It enables classification and quantification of airway inflammation associated with various pulmonary diseases such as asthma. Over the last decade, innumerable efforts have been made to identify biomarkers in EBC for diagnosis and management of asthma. The aim of this review is to consolidate information available to date, summarize findings from studies and identify potential biomarkers which need further refinement through translational research prior to application in clinical practice.
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Footnotes
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Invited topical review for the special issue on 'Carbon Monoxide and Exhaled Biomarkers: Diagnostic and Therapeutic Implications' for the Journal of Breath Research, editors Drs Ryter and Choi.