Topical Review

Multifunctional one-dimensional polymeric nanostructures for drug delivery and biosensor applications

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Published 26 July 2019 © 2019 IOP Publishing Ltd
, , Focus on Personalised Medicine and Theranostics Citation Sezin Sayin et al 2019 Nanotechnology 30 412001 DOI 10.1088/1361-6528/ab2e2c

0957-4484/30/41/412001

Abstract

Advances in nanotechnology in the last decades have paved the way for significant achievements in diagnosis and treatment of various diseases. Different types of functional nanostructures have been explored and utilized as tools for addressing the challenges in detection or treatment of diseases. In particular, one-dimensional nanostructures hold great promise in theranostic applications due to their increased surface area-to-volume ratios, which allow better targeting, increased loading capacity and improved sensitivity to biomolecules. Stable polymeric nanostructures that are stimuli-responsive, biocompatible and biodegradable are especially preferred for bioapplications. In this review, different synthesis techniques of polymeric one-dimensional nanostructures are explored and functionalization methods of these nanostructures for specific applications are explained. Biosensing and drug delibiovery applications of these nanostructures are presented in detail.

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