Abstract
Adenoviridae are rare causes of meningoencephalitis in both immunocompetent and immunocompromised hosts. In this article the authors report a case of adenoviral meningoencephalitis caused by serotype 26 and its identification, not described previously, in cerebrospinal fluid (CSF) by PCR and brain tissue by immunohistochemical staining.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Antoine JC, Pozetto B, Lucht F, Michel D, Gaudin OG, Rousset H (1987). Acute adenovirus encephalitis diagnosed by prolonged intrathecal antibody production. Lancet 1: 1382.
Baum SG (2000). Adenovirus. In Principles and Practice of Infectious Diseases 5th ed. Mandell GL, Bennett JE, Dolin R (ed). Churchill Licingstone: Philadelphia, pp, 1624–1630.
Bordigoni P, Carret AS, Venard V, Witz F, Le Faou A (2001). Treatment of adenovirus infections in patients undergoing allogeneic hematopoietic stem cell transplantation. Clin Infect Dis 32: 1290–1297.
Cardosa MJ, Krishnan S, Tio PH, Perera D, Wong SC (1999). Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. Lancet 354: 987–991.
Carter BA, Karpen SJ, Quiros-Tejeira RE, Chang IF, Clark BS, Demmler GJ, Heslop HE, Scott JD, Seu P, Goss JA (2002). Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient. Transplantation 74: 1050–1052.
Chatterjee NK, Samsonoff WA, Balasubramaniam N, Rush-Wilson K, Spargo W, Church TM (2000). Isolation and characterization of adenovirus 5 from the brain of an infant with fatal cerebral edema, Clin Infect Dis 31: 830–833.
Chou SM, Roos R, Burrell R, Gutmann L, Harley JB (1973). Subacute focal adenovirus encephalitis. J Neuropathol Exp Neurol 32: 34–50.
Duggan JM, Farrehi J, Duderstadt S, Turner NJ, Fekety R (1997). Treatment with ganciclovir of adenovirus pneumonia in a cardiac transplant patient. Am J Med 103: 439–440.
Haura EB, Winden MA, Proia AD, Trotter JE (2002). Fulminant hepatic failure due to disseminated adenovirus infection in a patient with chronic lymphocytic leukemia. Cancer Control 9: 248–253.
Heim A, Ebnet C, Harste G, Pring-Akerblom P (2003). Rapid and quantitative detection of human adenovirus DNA by real-time PCR. J Med Virol 70: 228–239.
Hierholzer JC (1992). Adenoviruses in the immunocompromised host. Clin Microbiol Rev 5: 262–274.
Hierholzer JC, Wigand R, Anderson LJ, Adrian T, Gold JW (1988). Adenoviruses from patients with AIDS: a plethora of serotypes and a description of five new serotypes of subgenus D (types 43–47). J Infect Dis 158: 804–813.
Horoupian DS, Pick P, Spigland I, Smith P, Portenoy R, Katzman R, Cho S (1984). Acquired immune deficiency syndrome and multiple tract degeneration in a homosexual man. Ann Neurol 15: 502–505.
Huttunen L (1970). Adenovirus type 7-associated encephalitis. Scand J Infect Dis 2: 151–153.
Janner D, Petru AM, Belchis D, Azimi PH (1990). Fatal adenovirus infection in a child with acquired immunodeficiency syndrome. Pediatr Infect Dis J 9: 434–436.
Kelsey DS (1978). Adenovirus meningoencephalitis. Pediatrics 61: 291–293.
Lord A, Bailey AS, Klapper PE, Snowden N, Khoo SH (2000). Impaired humoral responses to subgenus D adenovirusenovirus infections in HIV-positive patients. J Med Virol 62: 405–409.
Osamura T, Mizuta R, Yoshioka H, Fushiki S (1993). Isolation of adenovirus type 11 from the brain of a neonate with pneumonia and encephalitis. Eur J Pediatr 152: 496–499.
Ryan MA, Gray GC, Smith B, McKeehan JA, Hawksworth AW, Malasig MD (2002). Large epidemic of respiratory illness due to adenovirus types 7 and 3 in healthy young adults. Clin Infect Dis 34: 577–582.
Safrin S, Cherrington J, Jaffe HS (1997). Clinical uses of cidofovir. Rev Med Virol 7: 145–156.
Sakata H, Taketazu G, Nagaya K, Shirai M, Sugai R, Ikegami K, Maruyama S (1998). Outbreak of severe infection due to adenovirus type 7 in a paediatric ward in Japan. J Hosp Infect 39: 207–211.
Schnurr D, Bollen A, Crawford-Miksza L, Dondero ME, Yagi S (1995). Adenovirus mixture isolated from the brain of an AIDS patient with encephalitis. J Med Virol 47: 168–171.
Shields AF, Hackman RC, Fife KH, Corey L, Meyers JD (1985). Adenovirus infections in patients undergoing bone-marrow transplantation. N Engl J Med 312: 529–533.
Simila S, Jouppila R, Salmi A, Pohjonen R (1970). Encephaloningitis in children associated with an adenovirus type 7 epidemic. Acta Paediatr Scand 59: 310–316.
Studahl M, Bergstrom T, Hagberg L (1998). Acute viral encephalitis in adults—a prospective study. Scand J Infect Dis 30: 215–220.
West TE, Papasian CJ, Park BH, Parker SW (1985). Adenovirus type 2 encephalitis and concurrent Epstein-Barr virus infection in an adult man. Arch Neurol 42: 815–817.
Yamadera S, Yamashita K, Akatsuka M, Kato N, Inouye S (1998). Trend of adenovirus type 7 infection, an emerging disease in Japan. A report of the National Epidemiological Surveillance of Infectious Agents in Japan. Jpn J Med Sci Biol 51: 43–51.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Dubberke, E.R., Tu, B., Rivet, D.J. et al. Acute meningoencephalitis caused by adenovirus serotype 26. Journal of NeuroVirology 12, 235–240 (2006). https://doi.org/10.1080/13550280600846633
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1080/13550280600846633