Effect of the type of hydrophobic polymers on the size of nanoparticles obtained by emulsification–solvent evaporation
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Easy size control of polymer nanoparticles obtained by emulsification–evaporation technique in a microfluidic reactor
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2017, European Journal of Pharmaceutics and BiopharmaceuticsCitation Excerpt :Moreover, more hydrophobic polymers usually produce larger NPs. In accordance to our findings, previous studies showed that PCL produced larger NPs than PLGA [35,41]. The same was also observed for the more hydrophobic ester-terminated PLGA against its acid-terminated counterpart [42].
Formulation and in vitro evaluation of pH-responsive ethosomes for vaginal delivery of metronidazole
2014, Journal of Drug Delivery Science and TechnologyPoly(e{open}-caprolactone), Eudragit<sup>®</sup> RS 100 and poly(e{open}-caprolactone)/Eudragit<sup>®</sup> RS 100 blend submicron particles for the sustained release of the antiretroviral efavirenz
2013, Colloids and Surfaces B: BiointerfacesCitation Excerpt :Following the same trend, RS particles were the smallest of all the series with a size of 89.5 nm. These findings were in agreement with previous reports and they would rely on the fact that Eudragit® RS 100 plays the role of surfactant, stabilizing the system and favoring the generation of particles of smaller size [64]. When particles containing identical PCL/poly(methacrylate) ratio (1:1) were produced by the emulsion method, sizes were larger than those obtained by nanoprecipitation.
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