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Synthesis 1988; 1988(2): 138-140
DOI: 10.1055/s-1988-27492
DOI: 10.1055/s-1988-27492
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A One-Pot Synthesis of β-Acylenamines
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Publication History
Publication Date:
20 August 2002 (online)
β-Acylenamines (β-amino α,β-unsaturated ketones) 4 are prepared in good yields in a Mannich reaction by heating a mixture of ketone 1, triethyl orthoester 2 and secondary amine 3 in a pressure vessel.