Download PDF
Horm Metab Res 1975; 7(2): 152-157
DOI: 10.1055/s-0028-1093768
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Effect of Glucocorticoids on Lipoprotein Lipase Activity in Rat Heart and Adipose Tissue

P.  de Gasquet , E.  Pequignot-Planche , N. T. Tonnu , F. A. Diaby
  • Unité d'Etudes et de Recherches Diététiques, Institut National de la Santé et de la Recherche Médicale, Hôpital Bichat, Paris, France
Further Information

Publication History

Publication Date:
23 December 2008 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

Adipose tissue lipoprotein lipase activity in either fed or fasting rats was increased by glucocorticoid injection and decreased by adrenalectomy. The difference in enzyme activity between fed and fasting animals was unchanged by adrenalectomy.

Heart lipoprotein lipase activity in fed rats was increased by a single injection of glucocorticoid to the high level usually found in fasting rats. The rise in activity induced by fasting was reduced by adrenalectomy. The results suggest that the nutritional regulation of lipoprotein lipase activity in heart may partly be ascribed to glucocorticoids.

Key words

Adipose Tissue - Heart - Lipoprotein Lipase - Fasting - Adrenalectomy - Dexamethasone - Corticosterone - Cortisol - Glucagon

      >