Issue 72, 2015
From the journal:

Chemical Communications

Non-covalent phosphorylcholine coating reduces protein adsorption and phagocytic uptake of microparticles†

Anusha Garapatya  and  Julie A. Champion*a  

* Corresponding authors

a School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr. NW, Atlanta, GA 30332, USA
E-mail: julie.champion@chbe.gatech.edu
Web: http://champion.chbe.gatech.edu

Abstract

Phosphorylcholine co-polymer was assembled on model polystyrene microparticles through a simple, widely-applicable ethanol coating process. The coating rendered particles resistant to protein adsorption and phagocytosis by macrophages, making it useful for a range of biological applications.

Graphical abstract: Non-covalent phosphorylcholine coating reduces protein adsorption and phagocytic uptake of microparticles

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Article information

DOI
https://doi.org/10.1039/C5CC03459K
Article type
Communication
Submitted
26 Apr 2015
Accepted
27 Jul 2015
First published
03 Aug 2015

Chem. Commun., 2015,51, 13814-13817

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Non-covalent phosphorylcholine coating reduces protein adsorption and phagocytic uptake of microparticles

A. Garapaty and J. A. Champion, Chem. Commun., 2015, 51, 13814 DOI: 10.1039/C5CC03459K

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