Issue 12, 2015

Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications

Abstract

Imidazo[1,2-a]pyrazine acts as a versatile scaffold in organic synthesis and drug development. This review article is an effort to compile the progress made in synthetic methods and to illustrate its reactivity and multifarious biological activity. This review is mainly based on the pattern and position of the substitution, and should help the scientific community to bring about future developments.

Graphical abstract: Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications

Article information

Article type
Review Article
Submitted
02 Jul 2014
Accepted
09 Dec 2014
First published
10 Dec 2014

Org. Biomol. Chem., 2015,13, 3525-3555

Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications

R. Goel, V. Luxami and K. Paul, Org. Biomol. Chem., 2015, 13, 3525 DOI: 10.1039/C4OB01380H

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