Recent progress in biomedical applications of titanium dioxide

Zi Fei Yin; Long Wu; Hua Gui Yang; Yong Hua Su

doi:10.1039/C3CP43938K

Recent progress in biomedical applications of titanium dioxide

Zi Fei Yin,†^a Long Wu,†^b Hua Gui Yang*^b and Yong Hua Su*^a

* Corresponding authors

^a Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433 China
E-mail: suyh@smmu.edu.cn
Fax: +86 21 8187 1559
Tel: +86 21 8187 1569

^b Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China
E-mail: hgyang@ecust.edu.cn
Fax: +86 21 64252127
Tel: +86 21 64252127

Abstract

As one of the most common chemical materials, titanium dioxide (TiO₂) has been prepared and widely used for many years. Among all the applications, the biomedical applications of TiO₂ have motivated strong interest and intensive experimental and theoretical studies, owing to its unique photocatalytic properties, excellent biocompatibility, high chemical stability, and low toxicity. Advances in nanoscale science suggest that some of the current problems of life science could be resolved or greatly improved through applying TiO₂. This paper presents a critical review of recent advances in the biomedical applications of TiO₂, which includes the photodynamic therapy for cancer treatment, drug delivery systems, cell imaging, biosensors for biological assay, and genetic engineering. The characterizations and applications of TiO₂ nanoparticles, as well as nanocomposites and nanosystems of TiO₂, which have been prepared by different modifications to improve the function of TiO₂, are also offered in this review. Additionally, some perspectives on the challenges and new directions for future research in this emerging frontier are discussed.

Article information

https://doi.org/10.1039/C3CP43938K

Article type

Perspective

Submitted

06 Nov 2012

Accepted

25 Jan 2013

First published

28 Jan 2013

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Phys. Chem. Chem. Phys., 2013,15, 4844-4858

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Recent progress in biomedical applications of titanium dioxide

Z. Fei Yin, L. Wu, H. Gui Yang and Y. Hua Su, Phys. Chem. Chem. Phys., 2013, 15, 4844 DOI: 10.1039/C3CP43938K

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Physical Chemistry Chemical Physics

Recent progress in biomedical applications of titanium dioxide

Abstract

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Recent progress in biomedical applications of titanium dioxide

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