Issue 14, 2014

Catalytic asymmetric synthesis of 1,3-enyne scaffolds: design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology

Abstract

A novel catalytic enantioselective synthesis of functionalized 1,3-enynes has been developed featuring the design and synthesis of conjugated nitro dienynes as a useful new class of Michael acceptors. Moreover, a simple, yet flexible catalytic cascade approach to functionalized enantioenriched acyclic α,β-enones and cyclic dienones has also been developed.

Graphical abstract: Catalytic asymmetric synthesis of 1,3-enyne scaffolds: design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology

Supplementary files

Article information

Article type
Communication
Submitted
23 Nov 2013
Accepted
13 Dec 2013
First published
16 Dec 2013

Chem. Commun., 2014,50, 1745-1747

Author version available

Catalytic asymmetric synthesis of 1,3-enyne scaffolds: design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology

X. Li, F. Peng, M. Zhou, M. Mo, R. Zhao and Z. Shao, Chem. Commun., 2014, 50, 1745 DOI: 10.1039/C3CC48951E

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