Issue 5, 2014
From the journal:

Chemical Communications

Abasic site-binding ligands conjugated with cyanine dyes for “off–on” fluorescence sensing of orphan nucleobases in DNA duplexes and DNA–RNA hybrids†

Yusuke Sato,a   Megumi Kudo,a   Yu Toriyabe,a   Shota Kuchitsu,a   Chun-xia Wang,a   Seiichi Nishizawaa  and  Norio Teramae*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan
E-mail: teramae@m.tohoku.ac.jp
Fax: +81-22-795-6552
Tel: +81-22-795-6552

Abstract

A series of abasic site-binding ligands conjugated with cyanine dyes have been developed for “off–on” fluorescence sensing of an orphan nucleobase in DNA duplexes and DNA–RNA hybrids.

Graphical abstract: Abasic site-binding ligands conjugated with cyanine dyes for “off–on” fluorescence sensing of orphan nucleobases in DNA duplexes and DNA–RNA hybrids

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Article information

DOI
https://doi.org/10.1039/C3CC47717G
Article type
Communication
Submitted
08 Oct 2013
Accepted
30 Oct 2013
First published
31 Oct 2013

Chem. Commun., 2014,50, 515-517

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Abasic site-binding ligands conjugated with cyanine dyes for “off–on” fluorescence sensing of orphan nucleobases in DNA duplexes and DNA–RNA hybrids

Y. Sato, M. Kudo, Y. Toriyabe, S. Kuchitsu, C. Wang, S. Nishizawa and N. Teramae, Chem. Commun., 2014, 50, 515 DOI: 10.1039/C3CC47717G

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