Issue 26, 2013

Total synthesis of cyclic heptapeptide Rolloamide B

Abstract

The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide synthesis ligating native amino acids.

Graphical abstract: Total synthesis of cyclic heptapeptide Rolloamide B

Supplementary files

Article information

Article type
Communication
Submitted
30 Dec 2012
Accepted
23 Jan 2013
First published
24 Jan 2013

Chem. Commun., 2013,49, 2631-2633

Total synthesis of cyclic heptapeptide Rolloamide B

M. E. Khatib, M. Elagawany, E. Çalışkan, E. F. Davis, H. M. Faidallah, S. A. El-feky and A. R. Katritzky, Chem. Commun., 2013, 49, 2631 DOI: 10.1039/C3CC39291K

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