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Energy-transfer-based wavelength-shifting DNA probes with “clickable” cyanine dyes

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Abstract

The insertion of cyanine dye azides as energy donor dyes via postsynthetic “click”-type cycloaddition chemistry with e.g. a new thiazole orange azide combined with thiazole red yields dual emitting DNA probes with good fluorescence readout properties.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany

    Carolin Holzhauser, Moritz M. Rubner & Hans-Achim Wagenknecht

Authors
  1. Carolin Holzhauser
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  2. Moritz M. Rubner
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  3. Hans-Achim Wagenknecht
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Corresponding author

Correspondence to Hans-Achim Wagenknecht.

Additional information

Electronic supplementary information (ESI) available: Synthetic procedures for the TO azide and postsynthetic modifications, images of NMR and MS analyses

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Holzhauser, C., Rubner, M.M. & Wagenknecht, HA. Energy-transfer-based wavelength-shifting DNA probes with “clickable” cyanine dyes. Photochem Photobiol Sci 12, 722–724 (2013). https://doi.org/10.1039/c2pp25366f

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  • DOI: https://doi.org/10.1039/c2pp25366f

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