Issue 8, 2012
From the journal:

Analyst

Application of nanosized MCM-41 to fabrication of a nanostructured electrochemical sensor for the simultaneous determination of levodopa and carbidopa

Mohammad Mazloum-Ardakani,*a   Mohammad Ali Sheikh-Mohseni,a   Mohammad Abdollahi-Alibeika  and  Ali Benvidia  

* Corresponding authors

a Department of Chemistry, Faculty of Science, Yazd University, Yazd, I.R. Iran
E-mail: mazloum@yazduni.ac.ir
Fax: +00983518210644
Tel: +00983518211670

Abstract

A novel carbon paste electrode modified with nanosized mesoporous MCM-41 was prepared, and used as an electrochemical sensor to study the electro oxidation of levodopa (LD), carbidopa (CD) and their mixtures. Using differential pulse voltammetry (DPV), a highly selective and simultaneous determination of LD and CD has been explored at the modified electrode. The electrochemical sensor displayed a good resolving function for the overlapping voltammetric responses of LD and CD into two separate peaks with a potential difference of 370 mV. DPV peak currents of LD increased linearly with concentration over the 0.13 μM to 1250.00 μM range and exhibited a detection limit of 0.072 μM. Also, the proposed electrochemical sensor was used for the determination of LD and CD in some real samples, using the standard addition method.

Graphical abstract: Application of nanosized MCM-41 to fabrication of a nanostructured electrochemical sensor for the simultaneous determination of levodopa and carbidopa

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C2AN15795K
Article type
Paper
Submitted
30 Aug 2011
Accepted
10 Feb 2012
First published
08 Mar 2012

Analyst, 2012,137, 1950-1955

Permissions

Request permissions

Application of nanosized MCM-41 to fabrication of a nanostructured electrochemical sensor for the simultaneous determination of levodopa and carbidopa

M. Mazloum-Ardakani, M. A. Sheikh-Mohseni, M. Abdollahi-Alibeik and A. Benvidi, Analyst, 2012, 137, 1950 DOI: 10.1039/C2AN15795K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements