Issue 40, 2011
From the journal:

Chemical Communications

An efficient visible light controlled protein delivery system†

Leilei Luo,ab   Yong Guo,a   Juncheng Yang,b   Yijun Liu,b   Sheng Chu,ab   Fei Kong,ab   Ying Wang*ab  and  Zhigang Zou*a  

* Corresponding authors

a Eco-materials and Renewable Energy Research Center (REREC), National Laboratory of Solid State Microstructure, Nanjing University, Nanjing, People's Republic of China
E-mail: wangy@nju.edu.cn
Fax: +86-25-83686632
Tel: +86-25-83621219

b School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, People's Republic of China

Abstract

A visible light triggered protein delivery system has been assembled through hydroxyl coordinated onto titania nanoparticles. Biomolecules such as hemoglobin (Hb) can be controlled-released from the hybrid material TiO2–DB–Hb by switching visible light on/off. The released Hb not only retains its senior structure but also can fulfil the enzymatic bioactivity. Controlled delivery of Hb stems from the scission of the Ti–O coordination bond with the aid of photo-inducing electron transfer property of titania.

Graphical abstract: An efficient visible light controlled protein delivery system

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Article information

DOI
https://doi.org/10.1039/C1CC14100G
Article type
Communication
Submitted
08 Jul 2011
Accepted
08 Sep 2011
First published
19 Sep 2011

Chem. Commun., 2011,47, 11243-11245

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An efficient visible light controlled protein delivery system

L. Luo, Y. Guo, J. Yang, Y. Liu, S. Chu, F. Kong, Y. Wang and Z. Zou, Chem. Commun., 2011, 47, 11243 DOI: 10.1039/C1CC14100G

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