Issue 13, 2011
From the journal:

Chemical Communications

Synthesis of 3-indole derivatives by copper sulfonato Salen catalyzed three-component reactions in water†

Yanyang Qu,a   Fang Ke,a   Li Zhou,a   Zhengkai Li,a   Haifeng Xiang,a   Di Wuab  and  Xiangge Zhou*ab  

* Corresponding authors

a Institute of Homogeneous Catalysis, College of Chemistry, Sichuan University, Chengdu, China
E-mail: zhouxiangge@scu.edu.cn
Fax: +86-28-85412026
Tel: +86-28-85412026

b State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, China

Abstract

An efficient three-component reaction of indole, aldehyde, and malononitrile in water catalyzed by a copper(II) sulfonato Salen complex afforded 3-indole derivatives in good to excellent yields up to 97%.

Graphical abstract: Synthesis of 3-indole derivatives by copper sulfonato Salen catalyzed three-component reactions in water

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Article information

DOI
https://doi.org/10.1039/C0CC05695B
Article type
Communication
Submitted
21 Dec 2010
Accepted
28 Jan 2011
First published
21 Feb 2011

Chem. Commun., 2011,47, 3912-3914

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Synthesis of 3-indole derivatives by copper sulfonato Salen catalyzed three-component reactions in water

Y. Qu, F. Ke, L. Zhou, Z. Li, H. Xiang, D. Wu and X. Zhou, Chem. Commun., 2011, 47, 3912 DOI: 10.1039/C0CC05695B

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