Some novel reactions of the acetylenic carboxylic acid, 4-oxo-6-phenylhexynoic acid with succinic anhydride are described. One of the products of the reaction is a butyrolactone derivative. Transformation of 4-phenylbut-3-yn-2-one results in the formation of α,β-acetylenic-α′-alkoxy epoxides which are of interest as anti-tumour compounds.
S. E. Drewes, D. Douglass, D. G. S. Malissar, G. H. P. Roos and P. T. Kaye, J. Chem. Soc., Perkin Trans. 1, 1990, 1507 DOI: 10.1039/P19900001507
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