Reaction of cephalosporin V esters with 4-t-butyl iodobenzene difluoride is solvent dependent yielding the oxazoline (5) in acetonitrile and the fluorazetidinone (6) in dichloromethane; in contrast, the iodoarene dichloride gives the rearranged isothiazole (9).
J. J. Edmunds and W. B. Motherwell, J. Chem. Soc., Chem. Commun., 1989, 1348 DOI: 10.1039/C39890001348
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