Issue 11, 1979

Trimethylsilyl iodide as a peptide deblocking agent

Abstract

Removal of urethane and benzyl ether blocking groups from peptides is readily accomplished by treatment with trimethylsilyl iodide which is particularly useful for the debenzylation of O-benzyltyrosine without the formation of rearrangement products.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1979, 495-496

Trimethylsilyl iodide as a peptide deblocking agent

R. S. Lott, V. S. Chauhan and C. H. Stammer, J. Chem. Soc., Chem. Commun., 1979, 495 DOI: 10.1039/C39790000495

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements