Issue 6, 2012
From the journal:

Soft Matter

Synthesis of sodium alginate based sprayable new soft gel system†

Mahesh U. Chhatbar,a   Kamalesh Prasad,*a   Dharmesh R. Chejaraa  and  A. K. Siddhanta*a  

* Corresponding authors

a Marine Biotechnology and Ecology Discipline, CSIR-Central Salt & Marine Chemicals Research Institute (Council of Scientific & Industrial Research), G. B Marg, Bhavnagar, Gujarat, India
E-mail: kamlesh@csmcri.org, aks@csmcri.org
Fax: +91-278-2567562
Tel: +91-278-2569496

Abstract

Chemical reaction of sodium alginate (Na-Alg) with o-aminobenzoic acid (OABA) and m-aminobenzoic acid (MABA) in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride (EDC) afforded amide derivatives capable of forming viscous hydrogel systems exhibiting thixotropic behaviour. Characterization of the amide materials was done by employing FT-IR and 13C NMR, wherein amide formation between Na-Alg and OABA or MABA was confirmed. The thixotropic behaviour was evaluated by rheology and viscometry showing superior thixotropicity of OABA based amide to its MABA counterpart. The characteristic of the soft gel turning into a flowing liquid on gentle stirring predisposes it for possible application as a delivery system or sprayable gel material for transporting small active molecules to the targeted locations in health and personal care formulations.

Graphical abstract: Synthesis of sodium alginate based sprayable new soft gel system

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2SM06947D
Article type
Paper
Submitted
12 Oct 2011
Accepted
29 Nov 2011
First published
22 Dec 2011

Soft Matter, 2012,8, 1837-1844

Permissions

Request permissions

Synthesis of sodium alginate based sprayable new soft gel system

M. U. Chhatbar, K. Prasad, D. R. Chejara and A. K. Siddhanta, Soft Matter, 2012, 8, 1837 DOI: 10.1039/C2SM06947D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements