Issue 1, 2011

Synthesis of 5-arylidene-2,4-thiazolidinediones by Knoevenagel condensation catalyzed by baker's yeast

Abstract

An ecofriendly baker's yeast catalyzed Knoevenagel condensation of aromatic aldehydes and active methylene compounds has been performed. The developed protocol has been found to be applicable for obtaining 5-arylidene-2,4-thiazolidinediones, the precursors of hypoglycemic agents.

Graphical abstract: Synthesis of 5-arylidene-2,4-thiazolidinediones by Knoevenagel condensation catalyzed by baker's yeast

Article information

Article type
Letter
Submitted
07 Sep 2010
Accepted
19 Oct 2010
First published
09 Nov 2010

New J. Chem., 2011,35, 49-51

Synthesis of 5-arylidene-2,4-thiazolidinediones by Knoevenagel condensation catalyzed by baker's yeast

U. R. Pratap, D. V. Jawale, R. A. Waghmare, D. L. Lingampalle and R. A. Mane, New J. Chem., 2011, 35, 49 DOI: 10.1039/C0NJ00691B

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