Issue 1, 2010
From the journal:

Green Chemistry

An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1,3-diynes using catalyticCu(ii) and base†

Dong Wang,a   Jihui Li,a   Na Li,a   Tingting Gao,a   Sihua Houa  and  Baohua Chen*a  

* Corresponding authors

a Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou, 730000, P. R. China; State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, P. R. China
E-mail: chbh@lzu.edu.cn

Abstract

We report an environmentally friendly, efficient method for transforming terminal acetylenes into 1,3-diynes based on catalytic amounts of a Cu(II) salt and base under solvent-free conditions. The developed process conforms to the principles of ‘green’ chemistry and addresses the shortage of such methods for the synthesis of 1,3-diynes. The reaction is quite general and results in good yields. Interestingly, the system also allows the synthesis of unsymmetric 1,3-diynes by cross-coupling of two different terminal alkynes. Finally, the catalyst can also be recycled.

Graphical abstract: An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1,3-diynes using catalytic Cu(ii) and base

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B917448F
Article type
Communication
Submitted
24 Aug 2009
Accepted
19 Oct 2009
First published
30 Oct 2009

Green Chem., 2010,12, 45-48

Permissions

Request permissions

An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1,3-diynes using catalytic Cu(II) and base

D. Wang, J. Li, N. Li, T. Gao, S. Hou and B. Chen, Green Chem., 2010, 12, 45 DOI: 10.1039/B917448F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements