Issue 8, 2009
From the journal:

Green Chemistry

Highly selective N-Alkylation of amines promoted on silica: An efficient and recyclable surface

Basudeb Basu,*a   Susmita Paula  and  Ashis K. Nandaa  

* Corresponding authors

a Department of Chemistry, North Bengal University, Darjeeling, India
E-mail: basu_nbu@hotmail.com
Fax: +91 353 2699001
Tel: +91 353 2776381

Abstract

N-Alkylation of amines suffers from competing over alkylations. At the same time, use of strong base and other harsh conditions greatly limits providing a practical, generalized and selective procedure. Activated silica gel has been found to promote N-alkylations of amines. Here, we studied N-alkylation of amines with various types of alkyl halides, which finally constitute practical, highly selective and eco-friendly conditions for mono- or bis-alkylated amines at ambient temperature with recyclability of silica.

Graphical abstract: Highly selective N-Alkylation of amines promoted on silica: An efficient and recyclable surface

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B905878H
Article type
Communication
Submitted
24 Mar 2009
Accepted
28 Apr 2009
First published
13 May 2009

Green Chem., 2009,11, 1115-1120

Permissions

Request permissions

Highly selective N-Alkylation of amines promoted on silica: An efficient and recyclable surface

B. Basu, S. Paul and A. K. Nanda, Green Chem., 2009, 11, 1115 DOI: 10.1039/B905878H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements