Issue 1, 2008

Rapid C-carboxylation of nitro[11C]methane for the synthesis of ethyl nitro[2-11C]acetate

Abstract

The labelling synthesis of ethyl nitro[2-11C]acetate, a synthetic intermediate feasible for 11C-labelled PET tracers, by C-carboxylation of [11C]MeNO2 with 1-ethoxycarbonylbenzotriazole, and its simple application are presented.

Graphical abstract: Rapid C-carboxylation of nitro[11C]methane for the synthesis of ethyl nitro[2-11C]acetate

Article information

Article type
Communication
Submitted
17 Aug 2007
Accepted
22 Oct 2007
First published
31 Oct 2007

Mol. BioSyst., 2008,4, 53-55

Rapid C-carboxylation of nitro[11C]methane for the synthesis of ethyl nitro[2-11C]acetate

K. Kato, M. Zhang and K. Suzuki, Mol. BioSyst., 2008, 4, 53 DOI: 10.1039/B712734K

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