Issue 1, 2008
From the journal:

Green Chemistry

Making diazomethane accessible for R&D and industry: generation and direct conversion in a continuous micro-reactor set-up†

Michael Struempel,a   Bernd Ondruschka,a   Ralf Dauteb  and  Annegret Stark*a  

* Corresponding authors

a Friedrich-Schiller University of Jena, Institute for Technical Chemistry and Environmental Chemistry, Lessingstr. 12, 07743 Jena, Germany
E-mail: annegret.stark@uni-jena.de
Fax: +49 3641 948402
Tel: +49 3641 948413

b CHEMTEC LEUNA, Gesellschaft für Chemie und Technologie mbH, Am Haupttor, 06237 Leuna, Germany

Abstract

Micro-reaction technology offers a safe way to deliver diazomethane on demand both on the R&D and the industrially relevant scale, including in situ conversion to the desired product to avoid handling and storage of explosive diazomethane solutions, thus making this potent compound accessible for the pharmaceutical and fine chemical sector.

Graphical abstract: Making diazomethane accessible for R&D and industry: generation and direct conversion in a continuous micro-reactor set-up

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Article information

DOI
https://doi.org/10.1039/B710554A
Article type
Communication
Submitted
10 Jul 2007
Accepted
30 Oct 2007
First published
09 Nov 2007

Green Chem., 2008,10, 41-43

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Making diazomethane accessible for R&D and industry: generation and direct conversion in a continuous micro-reactor set-up

M. Struempel, B. Ondruschka, R. Daute and A. Stark, Green Chem., 2008, 10, 41 DOI: 10.1039/B710554A

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