Issue 16, 2007
From the journal:

Organic & Biomolecular Chemistry

A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines†

Sirirat Kumarn,a   Alexander J. Oelke,a   David M. Shaw,a   Deborah A. Longbottoma  and  Steven V. Ley*a  

* Corresponding authors

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: svl1000@cam.ac.uk
Fax: +44 1223 336442
Tel: +44 1223 336398

Abstract

A sequential, organocatalysed asymmetric reaction to access chiral 1,2-oxazines and chiral pyridazines is reported, which proceeds in moderate to good yields and good to excellent enantioselectivities.

Graphical abstract: A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines

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Article information

DOI
https://doi.org/10.1039/B708646F
Article type
Paper
Submitted
07 Jun 2007
Accepted
20 Jun 2007
First published
10 Jul 2007

Org. Biomol. Chem., 2007,5, 2678-2689

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A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines

S. Kumarn, A. J. Oelke, D. M. Shaw, D. A. Longbottom and S. V. Ley, Org. Biomol. Chem., 2007, 5, 2678 DOI: 10.1039/B708646F

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