Issue 11, 2006
From the journal:

Chemical Society Reviews

Imparting size, shape, and composition control of materials for nanomedicine

Larken E. Euliss,a   Julie A. DuPont,a   Stephanie Grattona  and  Joseph DeSimonea  

a Department of Chemistry, Chapel Hill, USA
E-mail: desimone@unc.edu
Fax: +1-919-962-5467
Tel: +1-919-962-2166

Abstract

This tutorial review presents an overview of strategies for the synthesis and fabrication of organic nanomaterials, specifically those with potential for use in medical applications. Examples include liposomes, micelles, polymer–drug conjugates and dendrimers. Methods of driving shape via “bottom-up” synthetic approaches and thermodynamics and kinetics are discussed. Furthermore, methods of driving shape via “top-down” physical and engineering techniques are also explored. Finally, a novel method (referred to as PRINT) used to produce nanoparticles that are shape-specific, can contain any cargo, and can be easily modified is examined along with its potential future role in nanomedicine.

Graphical abstract: Imparting size, shape, and composition control of materials for nanomedicine

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Article information

DOI
https://doi.org/10.1039/B600913C
Article type
Tutorial Review
Submitted
20 Jul 2006
First published
20 Sep 2006

Chem. Soc. Rev., 2006,35, 1095-1104

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Imparting size, shape, and composition control of materials for nanomedicine

L. E. Euliss, J. A. DuPont, S. Gratton and J. DeSimone, Chem. Soc. Rev., 2006, 35, 1095 DOI: 10.1039/B600913C

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