Issue 24, 2003
From the journal:

Chemical Communications

Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

Keitaro Yoshimoto,a   Chun-Yan Xu,a   Seiichi Nishizawa,a   Takanobu Haga,a   Hiroyuki Satakea  and  Norio Teramae*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan
E-mail: tera@anal.chem.tohoku.ac.jp
Fax: +81 22 2176552
Tel: +81 22 217 6549

Abstract

In combination with abasic site-containing oligodeoxynucleotides, 2-amino-4-oxopteridine (pterin) can selectively recognize guanine base over other nucleobases accompanied by fluorescence quenching, which allows clear detection of a guanine–adenine transition with the naked eye.

Graphical abstract: Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

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Article information

DOI
https://doi.org/10.1039/B309229A
Article type
Communication
Submitted
06 Aug 2003
Accepted
02 Oct 2003
First published
31 Oct 2003

Chem. Commun., 2003, 2960-2961

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Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

K. Yoshimoto, C. Xu, S. Nishizawa, T. Haga, H. Satake and N. Teramae, Chem. Commun., 2003, 2960 DOI: 10.1039/B309229A

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