Issue 13, 2003
From the journal:

Chemical Communications

DNA–Naphthyl Red conjugate as a visualizing probe of DNA hybridization†

Hiroyuki Asanuma,*ab   Hiromu Kashida,a   Xingguo Lianga  and  Makoto Komiyama*a  

* Corresponding authors

a Research Center for Advanced Science and Technology, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8904, Japan
E-mail: asanuma@mkomi.rcast.u-tokyo.ac.jp; komiyama@mkomi.rcast.u-tokyo.ac.jp
Fax: +81-3-5452-5202
Tel: +81-3-5452-5202

b PRESTO, Japan Science and Technology Corporation (JST), Kawaguchi 332-0012, Japan

Abstract

The Naphthyl Red moiety, conjugated to DNA, shows distinct chromism by hybridization with its complementary DNA. Single-stranded DNA involving the Naphthyl Red moiety exhibits an orange color and has λmax at 466 nm at pH 7.0. The absorption maximum is shifted towards 545 nm by the presence of its complementary DNA, and the color of the solution changes from orange to magenta accordingly.

Graphical abstract: DNA–Naphthyl Red conjugate as a visualizing probe of DNA hybridization

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Article information

DOI
https://doi.org/10.1039/B302875E
Article type
Communication
Submitted
18 Mar 2003
Accepted
09 May 2003
First published
29 May 2003

Chem. Commun., 2003, 1536-1537

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DNA–Naphthyl Red conjugate as a visualizing probe of DNA hybridization

H. Asanuma, H. Kashida, X. Liang and M. Komiyama, Chem. Commun., 2003, 1536 DOI: 10.1039/B302875E

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