Issue 14, 2001
From the journal:

Chemical Communications

Catalytic enantioselective addition of aromatic amines to enones: synthesis of optically active β-amino acid derivatives

Wei Zhuang,a   Rita G. Hazella  and  Karl Anker Jørgensen*a  

* Corresponding authors

a Center for Metal Catalysed Reactions, Department of Chemistry, Aarhus University, Aarhus C, Denmark.
E-mail: kaj@kemi.aau.dk

Abstract

A catalytic enantioselective addition of aromatic amines to enones has been developed; the potential of the reaction is shown for aromatic amines reacting with alkyl oxazolidinones in good yield and with moderate to excellent enantiomeric excess, and the transformation of the products to β-amino acid amides.

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Article information

DOI
https://doi.org/10.1039/B103334B
Article type
Communication
Submitted
12 Apr 2001
Accepted
18 May 2001
First published
14 Jun 2001

Chem. Commun., 2001, 1240-1241

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Catalytic enantioselective addition of aromatic amines to enones: synthesis of optically active β-amino acid derivatives

W. Zhuang, R. G. Hazell and K. A. Jørgensen, Chem. Commun., 2001, 1240 DOI: 10.1039/B103334B

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