Surface modification of chitosan membranesby alkane vapor plasma

Huanting Wang; Yue-E Fang; Yushan Yan

doi:10.1039/B009688L

Huanting Wang,^ab Yue-E Fang*^c and Yushan Yan*^b

* Corresponding authors

^a Department of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, P. R. China

^b Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA
E-mail: yushan.yan@ucr.edu
Fax: +1-(909) 787-2425
Tel: +1-(909) 787-2068

^c Department of Applied Chemistry, University of Science and Technology of China, Hefei, Anhui, P. R. China
Fax: +86-(551) 3631760

Abstract

Alkane (petroleum ether) vapor plasma technique was used for surface modification of chitosan membranes to control their permeation rate of water-soluble drugs and metabolites. Water contact angles of the chitosan surface increase from 13° to 23° after plasma treatment at 93 W for 60 min, and from 13° to 26° after plasma treatment at 119 W for 30 min, indicating reduced hydrophilicity of the membrane surface. Mechanical properties such as tensile strength and elongation-at-break of the chitosan membranes were also improved. In particular, there was a 6–7 fold increase in tensile strength in the wet state for the chitosan membrane treated at 93 W for 30 min. Permeation coefficients through the chitosan membrane plasma treated at 93 W for 30 min for urea, creatinine, uric acid, and cis-DDP decreased by 54.0%, 83.3%, 64.7% and 47.6%, respectively.

Article information

https://doi.org/10.1039/B009688L

Article type

Paper

Submitted

04 Dec 2000

Accepted

01 Mar 2001

First published

26 Mar 2001

Download Citation

J. Mater. Chem., 2001,11, 1374-1377

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