Issue 1, 2000
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Baker’s yeast mediated enantioselective synthesis of the bisabolene sesquiterpenes (+)-epijuvabione and (−)-juvabione

Claudio Fugantia  and  Stefano Serra*a  

* Corresponding authors

a Dipartimento di Chimica del Politecnico, Centro CNR per lo Studio delle Sostanze Organiche Naturali, Via Mancinelli, 7, Milano, Italy

Abstract

Fermenting baker’s yeast converts the unsaturated aldehydes 7 and 11 into the saturated alcohols 8 and 12, respectively. The microbial saturation of the double bond proceeds in high chemical yields and the stereoselectivity of the reduction is strongly influenced by the E∶Z ratio of the substrate. Enantiopure 8 and 12 are chiral building blocks for the synthesis of bisabolene sesquiterpenes and their usefulness is shown in the preparation of (+)-epijuvabione 1 and (−)-juvabione 3.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/A905977F
Article type
Paper
Submitted
23 Jul 1999
Accepted
25 Oct 1999
First published
24 Dec 1999

J. Chem. Soc., Perkin Trans. 1, 2000, 97-101

Permissions

Request permissions

Baker’s yeast mediated enantioselective synthesis of the bisabolene sesquiterpenes (+)-epijuvabione and (−)-juvabione

C. Fuganti and S. Serra, J. Chem. Soc., Perkin Trans. 1, 2000, 97 DOI: 10.1039/A905977F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements