Issue 8, 1999
From the journal:

New Journal of Chemistry

Hydroxylation of aromatic drugs by the electro-Fenton method. Formation and identification of the metabolites of Riluzole

Mehmet A. Oturan,   Jean Pinson,   Nihal Oturan  and  Dominique Deprez  

Abstract

The electro-Fenton method permits hydroxyl radicals to be produced by simultaneous electrochemical reduction of dioxygen and ferric ions. These hydroxyl radicals react with the neuroprotective drug Riluzole to give four identified hydroxylated compounds. These hydroxyl compounds are identical to the natural metabolites, the electrochemical behaviour of which is investigated. The electrochemically assisted Fenton reaction could therefore provide a convenient method for obtaining metabolites of aromatic drugs.

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Article information

DOI
https://doi.org/10.1039/A903791H
Article type
Paper

New J. Chem., 1999,23, 793-794

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Hydroxylation of aromatic drugs by the electro-Fenton method. Formation and identification of the metabolites of Riluzole

M. A. Oturan, J. Pinson, N. Oturan and D. Deprez, New J. Chem., 1999, 23, 793 DOI: 10.1039/A903791H

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