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Phosphodiesterase 11: a brief review of structure, expression and function

International Journal of Impotence Research volume 18, pages 501–509 (2006)Cite this article

Abstract

Phosphodiesterase 11 (PDE11) is the latest isoform of the phosphodiesterase family to be identified. Interest in PDE11 has increased recently because tadalafil, an oral phosphodiesterase 5 inhibitor, cross reacts with PDE11. The function of PDE11 remains largely unknown, but growing evidence points to a possible role in male reproduction. The published literature on PDE11 structure, function and expression is reviewed.

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Authors and Affiliations

  1. Department of Urology, University of Illinois at Chicago, Chicago, IL, USA

    A Makhlouf, A Kshirsagar & C Niederberger

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  1. A Makhlouf
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  2. A Kshirsagar
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  3. C Niederberger
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Correspondence to A Makhlouf.

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Makhlouf, A., Kshirsagar, A. & Niederberger, C. Phosphodiesterase 11: a brief review of structure, expression and function. Int J Impot Res 18, 501–509 (2006). https://doi.org/10.1038/sj.ijir.3901441

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