The use of programmed cell-death protein 1 (PD-1) inhibitors has become the standard-of-care approach for patients with advanced-stage, previously treated non-small-cell lung cancer. The inevitable adoption of these agents in the first-line setting is rapidly approaching, but the optimal strategy remains unclear. Two published clinical trial reports, examining different approaches, help to frame this question.
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Liu, S., Giaccone, G. First-line immunotherapy in lung cancer — taking the first step. Nat Rev Clin Oncol 13, 595–596 (2016). https://doi.org/10.1038/nrclinonc.2016.148
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DOI: https://doi.org/10.1038/nrclinonc.2016.148