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Effects of Protease Inhibitors on Protein Breakdown and Enzyme Induction in Starving Escherichia coli

Nature New Biology volume 234, pages 51–52 (1971)Cite this article

An Erratum to this article was published on 05 January 1972

Abstract

PROTEIN degradation is relatively slow in growing bacteria but much faster when there is no source of carbon or nitrogen1–3. These changes in degradative rates seem to be important for the adaptation of the cell to non-growing conditions and may be controlled by mechanisms similar to those regulating synthesis of ribosomal RNA4. Identification of selective inhibitors of protein breakdown could greatly facilitate study of the mechanisms of this process and its physiological significance.

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Authors and Affiliations

  1. Department of Physiology, Harvard Medical School, Boston, Massachusetts, 02115

    ALFRED L. GOLDBERG

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  1. ALFRED L. GOLDBERG
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GOLDBERG, A. Effects of Protease Inhibitors on Protein Breakdown and Enzyme Induction in Starving Escherichia coli. Nature New Biology 234, 51–52 (1971). https://doi.org/10.1038/newbio234051a0

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  • DOI: https://doi.org/10.1038/newbio234051a0

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