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Electron microscopy of frozen-hydrated biological material

Nature volume 319, pages 631–636 (1986)Cite this article

A Corrigendum to this article was published on 01 April 1986

Abstract

The electron microscopy of frozen-hydrated specimens has the potential to allow biological material to be examined in conditions very similar to the native state, and so has excited considerable interest. Although not all of the problems associated with the method have been solved, the technique has already provided important insights into macromolecular structure and assembly and promises to be a powerful tool for investigating the structure of cellular components and their interactions.

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Authors and Affiliations

  1. Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    Murray Stewart & Guy Vigers

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  1. Murray Stewart
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  2. Guy Vigers
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Stewart, M., Vigers, G. Electron microscopy of frozen-hydrated biological material. Nature 319, 631–636 (1986). https://doi.org/10.1038/319631a0

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